Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2)†
Abstract
Potent ROCK
* Corresponding authors
a
The Department of Drug Discovery, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida, USA
Fax: +813 745 6748
Tel: +813 745 6037
b Chemical Biology Core Facility, Moffitt Cancer Center, Tampa, Florida, USA
c Department of Oncological Sciences, University of South Florida, Tampa, Florida, USA
d Department of Chemistry, University of South Florida, Tampa, Florida, USA
e Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA
Potent ROCK
R. Pireddu, K. D. Forinash, N. N. Sun, M. P. Martin, S. Sung, B. Alexander, J. Zhu, W. C. Guida, E. Schönbrunn, S. M. Sebti and N. J. Lawrence, Med. Chem. Commun., 2012, 3, 699 DOI: 10.1039/C2MD00320A
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