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Issue 4, 2014
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Global gene expression distribution in non-cancerous complex diseases

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Abstract

For gene expression in non-cancerous complex diseases, we systemically evaluated the sensitivities of biological discoveries to violation of the common normalization assumption. Our results indicated that gene expression may be widely up-regulated in digestive system and musculoskeletal diseases. However, global signal intensities showed little difference in other four disease types.

Graphical abstract: Global gene expression distribution in non-cancerous complex diseases

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Publication details

The article was received on 23 Nov 2013, accepted on 23 Jan 2014 and first published on 24 Jan 2014


Article type: Communication
DOI: 10.1039/C3MB70524B
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Citation: Mol. BioSyst., 2014,10, 728-731
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    Global gene expression distribution in non-cancerous complex diseases

    Y. Wu, N. Jin, H. Zhu, C. Li, N. Liu, Y. Huang, Z. Miao, X. Bi, D. Wu, X. Chen, Y. Xiao, D. Hao, C. Li, B. Gong, S. Zhang, L. Zhuang, K. Li and D. Wang, Mol. BioSyst., 2014, 10, 728
    DOI: 10.1039/C3MB70524B

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