Issue 10, 2010
From the journal:

Molecular BioSystems

Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex†

Michelle R. Bond,‡ab   Chad M. Whitman‡ab  and  Jennifer J. Kohler*a  

* Corresponding authors

a Division of Translational Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, USA
E-mail: jennifer.kohler@utsouthwestern.edu
Fax: +1 214-648-4156
Tel: +1 214-648-1214

b Department of Chemistry, Stanford University, Stanford, USA

Abstract

When photoirradiated, an unnatural sialic acid analog can covalently capture the complex formed by ganglioside GM1 and cholera toxin subunit B.

Graphical abstract: Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex

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Article information

DOI
https://doi.org/10.1039/C0MB00069H
Article type
Communication
Submitted
22 Jun 2010
Accepted
25 Jun 2010
First published
13 Jul 2010

Mol. BioSyst., 2010,6, 1796-1799

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Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex

M. R. Bond, C. M. Whitman and J. J. Kohler, Mol. BioSyst., 2010, 6, 1796 DOI: 10.1039/C0MB00069H

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