Issue 8, 2010

Chemistry and biology of orexin signaling

Abstract

The orexins are neurohormones that, in concert with their cognate receptors, regulate a number of important physiological processes, including feeding, sleep, reward seeking and energy homeostasis. The orexin receptors have recently emerged as important drug targets. This review provides an overview of recent development in deciphering the biology of orexin signaling as well as efforts to manipulate orexin signaling pharmacologically.

Graphical abstract: Chemistry and biology of orexin signaling

Article information

Article type
Review Article
Submitted
23 Feb 2010
Accepted
05 May 2010
First published
07 Jun 2010

Mol. BioSyst., 2010,6, 1366-1375

Chemistry and biology of orexin signaling

T. Kodadek and D. Cai, Mol. BioSyst., 2010, 6, 1366 DOI: 10.1039/C003468A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements