Issue 12, 2008
From the journal:

Molecular BioSystems

Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT†

Sharon K. Hamilton,a   Mine R. Ikizler,b   Christian Wallen,a   Peter F. Wright*b  and  Eva Harth*a  

* Corresponding authors

a Departments of Chemistry and Pharmacology, 7619 Stevenson Center, Vanderbilt University, Nashville, USA
E-mail: eva.harth@vanderbilt.edu
Fax: +1 615 343 1234
Tel: +1 615 343 3405

b Department of Pediatrics, D-7219 MCN Vanderbilt University Medical Center, Nashville, USA
E-mail: peter.f.wright@dartmouth.edu
Fax: +1 615 343 9723
Tel: +1 615 322-3017

Abstract

IgG antibody–transporter conjugates enable intracellular uptake of biologically active IgG antibodies that inhibit viral mediated syncytia formation in respiratory syncytial virus green fluorescent protein (RSV-GFP) infected human epithelial cells (HEp-2).

Graphical abstract: Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT

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Article information

DOI
https://doi.org/10.1039/B816645E
Article type
Communication
Submitted
25 Sep 2008
Accepted
16 Oct 2008
First published
27 Oct 2008

Mol. BioSyst., 2008,4, 1209-1211

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Effective delivery of IgG-antibodies into infected cells via dendritic molecular transporter conjugate IgGMT

S. K. Hamilton, M. R. Ikizler, C. Wallen, P. F. Wright and E. Harth, Mol. BioSyst., 2008, 4, 1209 DOI: 10.1039/B816645E

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