Issue 10, 2008
From the journal:

Molecular BioSystems

Reciprocal chemical genetics for swift lead and target identification

Coenraad Kuijl,†a   Adriaan W. Tuin,†b   Hermen Overkleeftb  and  Jacques Neefjesa  

a Division of Tumor Biology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands
E-mail: j.neefjes@nki.nl

b Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands
E-mail: h.s.overkleeft@lic.leidenuniv.nl

Abstract

Reciprocal chemical genetics: correlation between chemical profile of in vivophenotypes and in vitro data of potential target genes leads to swift target identification.

Graphical abstract: Reciprocal chemical genetics for swift lead and target identification

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Article information

DOI
https://doi.org/10.1039/B803265N
Article type
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First published
24 Jul 2008

Mol. BioSyst., 2008,4, 1001-1008

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Reciprocal chemical genetics for swift lead and target identification

C. Kuijl, A. W. Tuin, H. Overkleeft and J. Neefjes, Mol. BioSyst., 2008, 4, 1001 DOI: 10.1039/B803265N

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