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Issue 20, 2015
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Engineering fluidic delays in paper-based devices using laser direct-writing

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Abstract

We report the use of a new laser-based direct-write technique that allows programmable and timed fluid delivery in channels within a paper substrate which enables implementation of multi-step analytical assays. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depth and/or the porosity of hydrophobic barriers which, when fabricated in the fluid path, produce controllable fluid delay. We have patterned these flow delaying barriers at pre-defined locations in the fluidic channels using either a continuous wave laser at 405 nm, or a pulsed laser operating at 266 nm. Using this delay patterning protocol we generated flow delays spanning from a few minutes to over half an hour. Since the channels and flow delay barriers can be written via a common laser-writing process, this is a distinct improvement over other methods that require specialist operating environments, or custom-designed equipment. This technique can therefore be used for rapid fabrication of paper-based microfluidic devices that can perform single or multistep analytical assays.

Graphical abstract: Engineering fluidic delays in paper-based devices using laser direct-writing

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Publication details

The article was received on 27 May 2015, accepted on 21 Aug 2015 and first published on 25 Aug 2015


Article type: Paper
DOI: 10.1039/C5LC00590F
Author version available: Download Author version (PDF)
Citation: Lab Chip, 2015,15, 4054-4061
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    Engineering fluidic delays in paper-based devices using laser direct-writing

    P. J. W. He, I. N. Katis, R. W. Eason and C. L. Sones, Lab Chip, 2015, 15, 4054
    DOI: 10.1039/C5LC00590F

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