Issue 3, 2015
From the journal:

Lab on a Chip

Nanostructured microfluidic digestion system for rapid high-performance proteolysis†

Gong Cheng,a   Si-Jie Hao,a   Xu Yua  and  Si-Yang Zheng*a  

* Corresponding authors

a Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA
E-mail: sxz10@psu.edu

Abstract

A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

Graphical abstract: Nanostructured microfluidic digestion system for rapid high-performance proteolysis

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Article information

DOI
https://doi.org/10.1039/C4LC01165A
Article type
Communication
Submitted
02 Oct 2014
Accepted
05 Dec 2014
First published
05 Dec 2014

Lab Chip, 2015,15, 650-654

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Nanostructured microfluidic digestion system for rapid high-performance proteolysis

G. Cheng, S. Hao, X. Yu and S. Zheng, Lab Chip, 2015, 15, 650 DOI: 10.1039/C4LC01165A

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