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Issue 4, 2013
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Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

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Abstract

Microfluidics and miniaturization of biosensors are fundamental for the development of point-of-care (PoC) diagnostic and analytical tools with the potential of decreasing reagent consumption and time of analysis while increasing portability. However, interfacing microfluidics with fluid control systems is still a limiting factor in practical implementation. We demonstrate an innovative capillary microfluidic design that allows sequential insertion of controlled volumes of liquids into a microfluidic channel with general applicability. The system requires only the placing of liquids at the corresponding inlets. Subsequently, the different solutions flow inside the microfluidic device sequentially and autonomously without the use of valves using integrated capillary pumps. The capillary microfluidic system is demonstrated with a model immunoassay.

Graphical abstract: Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

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Publication details

The article was received on 27 Jun 2012, accepted on 19 Nov 2012, published on 19 Nov 2012 and first published online on 19 Nov 2012


Article type: Technical Innovation
DOI: 10.1039/C2LC41083D
Citation: Lab Chip, 2013,13, 641-645
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    Control of sequential fluid delivery in a fully autonomous capillary microfluidic device

    P. Novo, F. Volpetti, V. Chu and J. P. Conde, Lab Chip, 2013, 13, 641
    DOI: 10.1039/C2LC41083D

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