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Issue 23, 2012
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A simple packed bed device for antibody labelled rare cell capture from whole blood

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Abstract

We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics. We characterized the capture of MCF-7 cells spiked into whole human blood using this system to demonstrate that enrichment and enumeration studies give results similar to in situ surface-modified devices while reducing fabrication and operation complexity.

Graphical abstract: A simple packed bed device for antibody labelled rare cell capture from whole blood

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Publication details

The article was received on 07 Aug 2012, accepted on 24 Sep 2012 and first published on 26 Sep 2012


Article type: Technical Innovation
DOI: 10.1039/C2LC41048F
Citation: Lab Chip, 2012,12, 4972-4975
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    A simple packed bed device for antibody labelled rare cell capture from whole blood

    J. G. Kralj, C. Arya, A. Tona, T. P. Forbes, M. S. Munson, L. Sorbara, S. Srivastava and S. P. Forry, Lab Chip, 2012, 12, 4972
    DOI: 10.1039/C2LC41048F

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