Issue 23, 2012
From the journal:

Lab on a Chip

High-throughput quantitative imaging of cell spreading dynamics by multi-step microscopy projection photolithography based on a cell-friendly photoresist†

Jong-Cheol Choia  and  Junsang Doh*ab  

* Corresponding authors

a Department of Mechanical Engineering, POSTECH, San31, Hyoja-dong, Nam-Gu, Pohang, Gyeongbuk, Korea
E-mail: muric@postech.ac.kr
Fax: +82 54 279 3199
Tel: +82 54 279 5555

b School of Interdisciplinary Bioscience and Bioengineering, Division of Integrative Biosciences and Biotechnology, POSTECH, San31, Hyoja-dong, Nam-Gu, Pohang, Gyeongbuk, Korea
E-mail: jsdoh@postech.ac.kr
Fax: +82 54 279 3199
Tel: +82 54 279 2189

Abstract

A new method for the high-throughput study of cell spreading dynamics is devised by multi-step microscopy projection photolithography based on a cell-friendly photoresist. By releasing a large number of rounded cells in single cell arrays and monitoring their spreading dynamics by interference reflection microscopy, a large number of cell spreading data can be acquired by a single experiment.

Graphical abstract: High-throughput quantitative imaging of cell spreading dynamics by multi-step microscopy projection photolithography based on a cell-friendly photoresist

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Article information

DOI
https://doi.org/10.1039/C2LC40695K
Article type
Communication
Submitted
20 Jun 2012
Accepted
26 Sep 2012
First published
26 Sep 2012

Lab Chip, 2012,12, 4964-4967

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High-throughput quantitative imaging of cell spreading dynamics by multi-step microscopy projection photolithography based on a cell-friendly photoresist

J. Choi and J. Doh, Lab Chip, 2012, 12, 4964 DOI: 10.1039/C2LC40695K

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