Issue 11, 2012

Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

Abstract

Manipulation of biological cells by acoustic radiation forces is often motivated by its improved biocompatibility relative to alternative available methods. On the other hand, it is well known that acoustic exposure is capable of causing damage to tissue or cells, primarily due to heating or cavitation effects. Therefore, it is important to define safety guidelines for the design and operation of the utilized devices. This tutorial discusses the biocompatibility of devices designed for acoustic manipulation of mammalian cells, and different methods for quantifying the cell viability in such devices.

Graphical abstract: Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

Additions and corrections

Article information

Article type
Focus
Submitted
24 Feb 2012
Accepted
04 Apr 2012
First published
04 May 2012

Lab Chip, 2012,12, 2018-2028

Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

M. Wiklund, Lab Chip, 2012, 12, 2018 DOI: 10.1039/C2LC40201G

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