Jump to main content
Jump to site search

Issue 9, 2007
Previous Article Next Article

Building up longitudinal concentration gradients in shallow microchannels

Author affiliations

Abstract

We demonstrate a compact and low consumption (60 nL) method for generating concentration gradients along microchannels with shallow parabolic cross-sections. The regimes of dispersion at work in such systems and the resulting concentration fields are described theoretically and experimentally. Experiments are performed in PDMS (polydimethylsiloxane) microchannels actuated by integrated valves. Detailed comparison between theory and experiment for the “short time” and “long time” regimes leads to excellent agreement. The system is used to successfully set up a series of isolated microchambers with mixtures of increasing solute concentrations, which may be a first step towards devices for screening.

Graphical abstract: Building up longitudinal concentration gradients in shallow microchannels

Back to tab navigation

Publication details

The article was received on 27 Apr 2007, accepted on 07 Jun 2007 and first published on 26 Jun 2007


Article type: Paper
DOI: 10.1039/B706340G
Citation: Lab Chip, 2007,7, 1154-1161
  •   Request permissions

    Building up longitudinal concentration gradients in shallow microchannels

    J. Goulpeau, B. Lonetti, D. Trouchet, A. Ajdari and P. Tabeling, Lab Chip, 2007, 7, 1154
    DOI: 10.1039/B706340G

Search articles by author

Spotlight

Advertisements