Issue 6, 2005
From the journal:

Lab on a Chip

A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS

Michael A. Powers,ad   Stephan T. Koev,ad   Arne Schleunitz,ad   Hyunmin Yi,e   Vildana Hodzic,a   William E. Bentley,cef   Gregory F. Payne,ef   Gary W. Rubloffbdf  and  Reza Ghodssi*adf  

* Corresponding authors

a Department of Electrical and Computer Engineering, College Park, USA

b Department of Materials Science and Engineering, College Park, USA

c Department of Chemical Engineering, College Park, USA

d Institute for Systems Research (ISR), College Park, USA

e University of Maryland Biotechnology Institute (UMBI), College Park, USA

f Bioengineering Program, University of Maryland, College Park, USA
E-mail: ghodssi@eng.umd.edu
Tel: 1-301-405-8158

Abstract

We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection.

Graphical abstract: A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS

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Article information

DOI
https://doi.org/10.1039/B503112E
Article type
Communication
Submitted
02 Mar 2005
Accepted
18 Apr 2005
First published
27 Apr 2005

Lab Chip, 2005,5, 583-586

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A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS

M. A. Powers, S. T. Koev, A. Schleunitz, H. Yi, V. Hodzic, W. E. Bentley, G. F. Payne, G. W. Rubloff and R. Ghodssi, Lab Chip, 2005, 5, 583 DOI: 10.1039/B503112E

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