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Issue 7, 2005
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An integrated disposable dye clad leaky waveguide sensor for μ-TAS applications

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Abstract

An integrated, disposable, dye clad leaky waveguide (DCLW) device has been fabricated and tested for both refractive index and fluorescence detection in μ-TAS applications. The chip comprises the required flow geometry and optical coupling elements in a robust device that is relatively simple and inexpensive to fabricate. Disposable DCLW chips were fabricated at room temperature by spin-coating both the dye and silica sol-gel waveguiding layers on a polymer substrate which contained injection moulded grating coupler. These devices have been designed to increase the interaction of the evanescent field light at the channel wall and with the sample in the channel. The DCLW device has been used to detect changes in the refractive index of different percentages of glycerol solutions and to detect low concentrations down to 10−12 M fluorescein using a grating coupler.

Graphical abstract: An integrated disposable dye clad leaky waveguide sensor for μ-TAS applications

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Publication details

The article was received on 15 Feb 2005, accepted on 15 Apr 2005 and first published on 19 May 2005


Article type: Paper
DOI: 10.1039/B502361K
Citation: Lab Chip, 2005,5, 772-777
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    An integrated disposable dye clad leaky waveguide sensor for μ-TAS applications

    M. Zourob, S. Mohr, P. R. Fielden and N. J. Goddard, Lab Chip, 2005, 5, 772
    DOI: 10.1039/B502361K

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