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Issue 40, 2012
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Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

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Abstract

We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12 000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.

Graphical abstract: Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(iii) complexes

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Publication details

The article was received on 27 Jul 2012, accepted on 30 Aug 2012 and first published on 14 Sep 2012


Article type: Communication
DOI: 10.1039/C2JM34999J
Citation: J. Mater. Chem., 2012,22, 21382-21386
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    Polymer–gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

    M. Beija, Y. Li, H. T. Duong, S. Laurent, L. V. Elst, R. N. Muller, A. B. Lowe, T. P. Davis and C. Boyer, J. Mater. Chem., 2012, 22, 21382
    DOI: 10.1039/C2JM34999J

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