Issue 42, 2012
From the journal:

Journal of Materials Chemistry

pH responsive smart carrier of [60] fullerene with 6-amino-cyclodextrin inclusion complex for photodynamic therapy†

Kazuyuki Nobusawa,*d   Motofusa Akiyama,e   Atsushi Ikedad  and  Masanobu Naito*abcd  

* Corresponding authors

a TU–NIMS Joint Research Center, School of Materials Science and Engineering, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, P.R. China

b National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-044, Japan
E-mail: NAITO.Masanobu@nims.go.jp
Tel: +81 029 860 4783

c JST PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan

d Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan
E-mail: n-kazuyu@ms.naist.jp
Fax: +81 743 72 6018
Tel: +81 743 72 6017

e Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 113-8551, Japan

Abstract

A new pH responsive smart carrier of C60 was prepared with 6-amino-γ-cyclodextrin (ACD) for photodynamic therapy. C60 was rapidly released from its inclusion complex with ACD at pH 6.7, due to electrostatic repulsion between ammonium groups, followed by a rapid C60 release at slightly acidic cancer cell surfaces.

Graphical abstract: pH responsive smart carrier of [60] fullerene with 6-amino-cyclodextrin inclusion complex for photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C2JM34791A
Article type
Paper
Submitted
20 Jul 2012
Accepted
18 Sep 2012
First published
20 Sep 2012

J. Mater. Chem., 2012,22, 22610-22613

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pH responsive smart carrier of [60] fullerene with 6-amino-cyclodextrin inclusion complex for photodynamic therapy

K. Nobusawa, M. Akiyama, A. Ikeda and M. Naito, J. Mater. Chem., 2012, 22, 22610 DOI: 10.1039/C2JM34791A

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