Issue 26, 2011
From the journal:

Journal of Materials Chemistry

pH-responsive mitoxantrone (MX) delivery using mesoporous silicananoparticles (MSN)†

Yanhang Ma,‡a   Lin Zhou,‡b   Haoquan Zheng,a   Lei Xing,a   Chenguang Li,a   Jinghao Cui*b  and  Shunai Che*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China
E-mail: chesa@sjtu.edu.cn
Fax: +86-21-5474-1297
Tel: +86-21-5474-2852

b Department of Pharmaceutics, College of Pharmaceutical Science, Soochow University, 199 Renai Road, Suzhou, China
E-mail: jhcui@suda.edu.cn
Fax: +86-512-6588-2077

Abstract

The pH-responsive delivery of an anti-cancer drug, MX, has been successfully achieved by varying the strength of the electrostatic interaction between the negatively charged silicate and positively charged MX, using MSN.

Graphical abstract: pH-responsive mitoxantrone (MX) delivery using mesoporous silica nanoparticles (MSN)

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Article information

DOI
https://doi.org/10.1039/C1JM10750J
Article type
Communication
Submitted
19 Feb 2011
Accepted
04 May 2011
First published
20 May 2011

J. Mater. Chem., 2011,21, 9483-9486

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pH-responsive mitoxantrone (MX) delivery using mesoporous silica nanoparticles (MSN)

Y. Ma, L. Zhou, H. Zheng, L. Xing, C. Li, J. Cui and S. Che, J. Mater. Chem., 2011, 21, 9483 DOI: 10.1039/C1JM10750J

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