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Issue 8, 2011
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Thermo-responsive protein adsorbing materials for purifying pharmaceutical protein on exposed charging surface

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Abstract

Thermo-responsive anionic terpolymer brushes with high selectivity for proteins were prepared though surface-initiated ATRP. Utilizing these terpolymer brushes, pure lysozyme was successfully separated from egg-white. Thus, the prepared thermo-responsive terpolymer brush is an effective separation tool for the pharmaceutical and biotechnological industries that produce valuable proteins.

Graphical abstract: Thermo-responsive protein adsorbing materials for purifying pharmaceutical protein on exposed charging surface

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Publication details

The article was received on 13 Oct 2010, accepted on 18 Nov 2010 and first published on 24 Dec 2010


Article type: Paper
DOI: 10.1039/C0JM03453C
Citation: J. Mater. Chem., 2011,21, 2590-2593
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    Thermo-responsive protein adsorbing materials for purifying pharmaceutical protein on exposed charging surface

    K. Nagase, S. F. Yuk, J. Kobayashi, A. Kikuchi, Y. Akiyama, H. Kanazawa and T. Okano, J. Mater. Chem., 2011, 21, 2590
    DOI: 10.1039/C0JM03453C

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