Issue 3, 2011
From the journal:

Journal of Materials Chemistry

Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling†

David Díaz Díaz,*ab   Emmanuelle Morin,cd   Eva M. Schön,a   Ghyslain Budin,d   Alain Wagnerd  and  Jean-Serge Remyc  

* Corresponding authors

a Institut für Organische Chemie, Universität Regensburg, Universitätsstr. 31, Regensburg, Germany
E-mail: David.Diaz@chemie.uni-regensburg.de
Fax: +49 941 9434121
Tel: +49 941 9434373

b Instituto de Ciencias de Materiales de Aragón, CSIC-Universidad de Zaragoza, Pedro Cerbuna 12, Zaragoza, Spain

c Chimie Génétique, Faculté de Pharmacie, Strasbourg, France

d Laboratory of Functionnal ChemoSystems, UMR 7199, Faculté de Pharmacie, Strasbourg, France

Abstract

We describe a general user-friendly platform for fine-tuning the drug release properties of low-molecular-weight hydrogels by a combination of supramolecular co-assembly of complementary molecular structures and controlled photochemical thiol–ene cross-linking. Other critical features such as thermomechanical stability and morphology of the nanostructured hydrogels are also tailored by this approach.

Graphical abstract: Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0JM03399E
Article type
Communication
Submitted
08 Oct 2010
Accepted
03 Nov 2010
First published
22 Nov 2010

J. Mater. Chem., 2011,21, 641-644

Permissions

Request permissions

Tailoring drug release profile of low-molecular-weight hydrogels by supramolecular co-assembly and thiol–ene orthogonal coupling

D. D. Díaz, E. Morin, E. M. Schön, G. Budin, A. Wagner and J. Remy, J. Mater. Chem., 2011, 21, 641 DOI: 10.1039/C0JM03399E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements