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Issue 1, 2009
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Advances in combinatorial and high-throughput screening of biofunctional polymers for gene delivery, tissue engineering and anti-fouling coatings

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Abstract

The past ten years have witnessed the emergence of a new set of tools, combinatorial and high-throughput screening, in polymeric biomaterials development. These tools, developed initially in the drug-discovery industry, and later applied to catalysts and inorganic materials, allow orders of magnitude increases in the rate of exploration and characterization of new materials. This feature article covers recent examples of high-throughput and combinatorial studies of biofunctional polymers. Biofunctional polymers exhibit chemistry or physical properties specifically designed to function in a biological context. Examples include polymers with unique binding affinities or surface physical properties for gene and drug delivery, tissue engineering scaffolds, anti-fouling and anti-bacterial coatings, and biocatalytic applications.

Graphical abstract: Advances in combinatorial and high-throughput screening of biofunctional polymers for gene delivery, tissue engineering and anti-fouling coatings

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Publication details

The article was received on 22 May 2008, accepted on 22 Aug 2008 and first published on 23 Oct 2008


Article type: Feature Article
DOI: 10.1039/B808649D
Citation: J. Mater. Chem., 2009,19, 34-45
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    Advances in combinatorial and high-throughput screening of biofunctional polymers for gene delivery, tissue engineering and anti-fouling coatings

    J. C. Meredith, J. Mater. Chem., 2009, 19, 34
    DOI: 10.1039/B808649D

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