Issue 11, 2007

On line coupling HPLC and quartz surface-induced luminescence FPD with hydride generation and microporous membrane gas–liquid separator as interface for the speciation of methyltins

Abstract

A novel on-line coupled high performance liquid chromatography (HPLC)-hydride generation (HG)-microporous membrane gas–liquid separator (MGLS)-quartz surface-induced luminescence flame photometric detector (QSIL-FPD) system was developed for the speciation of methyltins. Methyltin compounds were separated by HPLC, and then on-line reacted with potassium borohydride to generate volatile hydride products. The volatile derivatization products were in-line separated from the liquid matrix with MGLS and further introduced into the cheap and specific QSIL-FPD for detection. With a mobile phase of 70% methanol, 3% acetic acid and 27% water, which contains 0.1% tropolone as complexant, at a 0.3 mL min−1 flow rate, monomethyltin (MMT), dimethyltin (DMT) and trimethyltin (TMT) were baseline separated in less than 13 minutes by reversed phase HPLC. Both derivatization reagents, 0.5% KBH4 and 2% acetic acid, were introduced into the system simultaneously at the same flow rate of 0.4 mL min−1. Calibration curves, based on peak heights vs. concentration, were linear in the range of 1–100 ng mL−1 of methyltins with correlation coefficients of 0.9980, 0.9911 and 0.9975 for MMT, DMT and TMT, respectively. The relative standard deviations measured at 10 ng mL−1 (for MMT and DMT) and 5 ng mL−1 (for TMT) level were in the range of 2.0–3.8% (n = 3) for the studied methyltins, and the calculated detection limits (S/N = 3) for MMT, DMT and TMT were 1.69, 0.51 and 0.36 ng mL−1, respectively. This developed method was applied to the speciation of methyltins in seawater with spiked recovery in the range of 95.9–100.7%. This method was also applied to the determination of the methyltin compounds in wastewater and the process solutions (the mixtures of methyltin trichloride and dimethyltin dichloride) which are the intermediates of methyltin mercaptide polyvinyl chloride heat stabilizer from a chemical factory.

Graphical abstract: On line coupling HPLC and quartz surface-induced luminescence FPD with hydride generation and microporous membrane gas–liquid separator as interface for the speciation of methyltins

Article information

Article type
Paper
Submitted
21 Mar 2007
Accepted
19 Jun 2007
First published
13 Jul 2007

J. Anal. At. Spectrom., 2007,22, 1420-1426

On line coupling HPLC and quartz surface-induced luminescence FPD with hydride generation and microporous membrane gas–liquid separator as interface for the speciation of methyltins

G. Zhai, J. Liu, G. Jiang, B. He and Q. Zhou, J. Anal. At. Spectrom., 2007, 22, 1420 DOI: 10.1039/B704283C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements