Ethyl 3-amino-3-cyano-2-methylacrylate, a product from the reaction of ethyl 2-bromopropionate with sodium cyanide
Abstract
Ethyl 2-bromopropionate reacts with sodium cyanide to give ethyl 2-cyanopropionate (30%), a mixture of diastereoisomers of diethyl 2-cyano-2,3-dimethylsuccinate (10%), and ethyl 3-amino-3-cyano-2-methylacrylate (10%)(1).