Issue 10, 2013

Bridging racemic lactate esters with stereoselective polylactic acid using commercial lipase catalysis

Abstract

A productive and enantioselective hydrolysis of racemic mixtures of lactate esters with commercial Candida rugosa lipase was performed. This step contributes to a novel envisioned route for stereoselective PLA production by combining recent chemocatalytic developments with this biocatalytic contribution, foreseeing two separate L- and D-lactate enantiomer streams. A study of the hydrolysis kinetics identified an unexpected rate determining step at the origin of an unprecedented ester reactivity order.

Graphical abstract: Bridging racemic lactate esters with stereoselective polylactic acid using commercial lipase catalysis

Supplementary files

Article information

Article type
Paper
Submitted
22 Jul 2013
Accepted
13 Aug 2013
First published
14 Aug 2013

Green Chem., 2013,15, 2817-2824

Bridging racemic lactate esters with stereoselective polylactic acid using commercial lipase catalysis

P. Van Wouwe, M. Dusselier, A. Basiç and B. F. Sels, Green Chem., 2013, 15, 2817 DOI: 10.1039/C3GC41457D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements