Jump to main content
Jump to site search

Issue 3, 2012
Previous Article Next Article

A practicable environmentally benign one-pot synthesis of 2-arylbenzofurans at room temperature

Author affiliations

Abstract

An environmentallyfriendly one-pot synthesis of 2-arylbenzofurans under ambient temperature has been developed. It features an ortho-hydroxyl group assisted Wittig reaction of substituted salicylaldehyde followed by an in situ oxidative cyclization. Its advantages include readily available and non-hazardous materials, benign reaction conditions (room temperature, green solvent and one-pot manner), easy work-up and high overall yields. Utilizing this methodology, various 2-aryl-benzofurans including four natural products have been synthesized.

Graphical abstract: A practicable environmentally benign one-pot synthesis of 2-arylbenzofurans at room temperature

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Sep 2011, accepted on 24 Nov 2011 and first published on 13 Jan 2012


Article type: Paper
DOI: 10.1039/C2GC16181H
Citation: Green Chem., 2012,14, 695-701
  •   Request permissions

    A practicable environmentally benign one-pot synthesis of 2-arylbenzofurans at room temperature

    L. Liao, G. Shen, X. Zhang and X. Duan, Green Chem., 2012, 14, 695
    DOI: 10.1039/C2GC16181H

Search articles by author

Spotlight

Advertisements