Issue 11, 2009
From the journal:

Green Chemistry

An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series†

Anita Cohen,a   Maxime D. Crozet,a   Pascal Rathelota  and  Patrice Vanelle*a  

* Corresponding authors

a Laboratoire de Pharmaco-Chimie Radicalaire, LPCR, Faculté de Pharmacie, Universités d'Aix-Marseille I, II, III-CNRS 6264: Laboratoire Chimie Provence, 27 Boulevard Jean Moulin, Marseille Cedex 05, France
E-mail: patrice.vanelle@pharmacie.univ-mrs.fr
Fax: +33-4-91-79-46-77
Tel: +33-4-91-83-55-80

Abstract

A new simple, rapid and high yielding synthesis of various 5-substituted thiazoles by Suzuki–Miyaura cross-coupling reaction is described using microwave irradiation in aqueous medium without organic co-solvent in the presence of tetrabutylammonium bromide.

Graphical abstract: An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

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Article information

DOI
https://doi.org/10.1039/B916123F
Article type
Communication
Submitted
25 May 2009
Accepted
10 Aug 2009
First published
03 Sep 2009

Green Chem., 2009,11, 1736-1742

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An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

A. Cohen, M. D. Crozet, P. Rathelot and P. Vanelle, Green Chem., 2009, 11, 1736 DOI: 10.1039/B916123F

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