NMR determination of EPR hyperfine coupling constants of some 5-(n-alkyl)-1,1,3,3-tetrakis(trideuteriomethyl)isoindolin-2-yloxyls

Abstract

2D ¹H–¹³C chemical shift correlation spectroscopy has been used to determine some small ¹H and ¹³C EPR hyperfine interaction constants in some 5-(n-alkyl)isoindolin-2-yloxyl radicals. In the methodology used, it was necessary to measure the chemical shifts of both the isoindolines and of the cognate isoindolin-2-yloxyl radicals. The latter n-alkyl-substituted radicals have considerable potential as EPR spin probes in lipid systems.