Issue 10, 2011

Dietary chromones as antioxidant agents—the structural variable

Abstract

This study reports an evaluation of the free radical scavenging ability of a series of chromone derivatives, in the light of their structural features and conformational behaviour. The 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) test for the assessment of radical scavenging properties was applied, and the interpretation of the experimental results was assisted by ab initio theoretical approaches that allowed relevant parameters, such as the enthalpy of formation of the radical species, to be predicted. From the eighteen tested compounds, three—fisetin, luteolin and quercetin—are shown to act as effective antiradicals. Consistent structure–activity relationships (SARs) were established regarding the antioxidant role of this type of chromone-based system.

Graphical abstract: Dietary chromones as antioxidant agents—the structural variable

Article information

Article type
Paper
Submitted
03 Jun 2011
Accepted
23 Jul 2011
First published
07 Sep 2011

Food Funct., 2011,2, 595-602

Dietary chromones as antioxidant agents—the structural variable

M. M. Dias, N. F. L. Machado and M. P. M. Marques, Food Funct., 2011, 2, 595 DOI: 10.1039/C1FO10098J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements