Study of ternary complexes of copper(II) containing tertiary amines and adenosine-5′-triphosphate in dioxan–water media

Abstract

The proton–ligand formation constants of adenosine-5′-triphosphate (atp), the formation constants of the binary complexes [Cu(atp)], and the formation constants of the ternary complexes [CuA(atp)], where A = 2,2′-bipyridyl, 1,10-phenanthroline, 2-(2′-pyridyl)benzimidazole, or 2-(2′-pyridyl)imidazoline have been determined in dioxan–water (1:2 v/v and 1:1 v/v) solutions, and 0.2 mol dm^–3 NaClO₄, at 30 °C. It is observed that the intramolecular hydrophobic stacking interaction between the tertiary amine and the basic part of atp is reduced in dioxan solution leading to negative Δ log K values in some cases.