Issue 11, 2010
From the journal:

Chemical Society Reviews

Organocatalytic strategies for the asymmetric functionalization of indoles†

Giuseppe Bartoli,*a   Giorgio Bencivennia  and  Renato Dalpozzob  

* Corresponding authors

a Università di Bologna, Dipartimento di Chimica Organica “A. Mangini”, viale Risorgimento 4, I-40136 Bologna, Italy
E-mail: giuseppe.bartoli@unibo.it
Fax: +39-051-20-93654
Tel: +39-051-20-93617

b Università della Calabria, Dipartimento di Chimica, Ponte Bucci cubo 12/c, I-87030 Arcavacata di Rende (Cs), Italy
E-mail: dalpozzo@unical.it
Fax: +39-0984-49-3077
Tel: +39-0984-49-2055

Abstract

The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009 (127 references).

Graphical abstract: Organocatalytic strategies for the asymmetric functionalization of indoles

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Article information

DOI
https://doi.org/10.1039/B923063G
Article type
Critical Review
Submitted
03 Mar 2010
First published
17 Sep 2010

Chem. Soc. Rev., 2010,39, 4449-4465

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Organocatalytic strategies for the asymmetric functionalization of indoles

G. Bartoli, G. Bencivenni and R. Dalpozzo, Chem. Soc. Rev., 2010, 39, 4449 DOI: 10.1039/B923063G

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