Issue 2, 2010
From the journal:

Chemical Society Reviews

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents†

Devdutt Chaturvedi,a   Abhishek Goswami,a   Partha Pratim Saikia,a   Nabin C. Barua*a  and  Paruchuri G. Raoa  

* Corresponding authors

a Natural Products Chemistry Division, North-East Institute of Science & Technology, Assam, India
E-mail: baruanc@rrljorhat.res.in
Fax: 91-376-2370011

Abstract

In this tutorial review, an effort towards presentation of a comprehensive account of the recent developments on various kinds of artemisinin derivatives including artemisinin dimers, trimers and tetramers has been made and their efficacy towards malaria parasites and different cancer cells lines was compared with that of artemisinins, and various other anti-malarial and anti-cancer drugs. It is expected that this review will provide first-hand information on artemisinin chemistry to organic/medicinal chemists, and pharmacologists working on anticancer and anti-malarial drug development.

Graphical abstract: Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

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Article information

DOI
https://doi.org/10.1039/B816679J
Article type
Tutorial Review
Submitted
03 Feb 2009
First published
24 Aug 2009

Chem. Soc. Rev., 2010,39, 435-454

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Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

D. Chaturvedi, A. Goswami, P. Pratim Saikia, N. C. Barua and P. G. Rao, Chem. Soc. Rev., 2010, 39, 435 DOI: 10.1039/B816679J

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