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Issue 2, 2007
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Biologically active, synthetic ion transporters

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The compelling chemical goal of modeling protein channel behavior has led to synthetic compounds that are true ion channels. Although they largely lack the selectivity and sophistication of highly evolved proteins, they successfully perform a variety of biological functions. This tutorial review describes these novel structures and their activity in living systems. Different channel structures show antibacterial to anticancer activity when tested against a variety of cell types.

Graphical abstract: Biologically active, synthetic ion transporters

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The article was received on 30 Aug 2006 and first published on 05 Dec 2006

Article type: Tutorial Review
DOI: 10.1039/B605910B
Citation: Chem. Soc. Rev., 2007,36, 378-389
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    Biologically active, synthetic ion transporters

    G. W. Gokel and I. A. Carasel, Chem. Soc. Rev., 2007, 36, 378
    DOI: 10.1039/B605910B

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