Jump to main content
Jump to site search

Issue 6, 2004
Previous Article Next Article

Combined approach using capillary electrophoresis and NMR spectroscopy for an understanding of enantioselective recognition mechanisms by cyclodextrins

Author affiliations

Abstract

This tutorial review describes the contribution of chiral capillary electrophoresis in combination with other instrumental techniques, especially nuclear magnetic resonance spectroscopy, to a better understanding of the chiral recognition mechanisms by cyclodextrins. Aspects such as affinity pattern of enantiomers towards various cyclodextrins as well as the stoichiometry of the resulting complexes, the equilibrium constants and the structure of complexes are addressed. In addition to the aforementioned techniques, the usefulness of complementary instrumental and molecular modeling techniques for an understanding of the chiral recognition mechanisms of cyclodextrins is also illustrated.

Graphical abstract: Combined approach using capillary electrophoresis and NMR spectroscopy for an understanding of enantioselective recognition mechanisms by cyclodextrins

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 02 Feb 2004 and first published on 05 Jul 2004


Article type: Tutorial Review
DOI: 10.1039/B111412N
Citation: Chem. Soc. Rev., 2004,33, 337-347
  •   Request permissions

    Combined approach using capillary electrophoresis and NMR spectroscopy for an understanding of enantioselective recognition mechanisms by cyclodextrins

    B. Chankvetadze, Chem. Soc. Rev., 2004, 33, 337
    DOI: 10.1039/B111412N

Search articles by author