Issue 7, 2014

Cucurbit[7]uril assisted ultraviolet to visible fluorescence switch of a heart medicine

Abstract

Host–guest interactions between cucurbit[7]uril (CB7) and a cardiotonic drug, milrinone, have been explored using steady state and pico-second time-resolved techniques. A novel fluorescence switch from ultraviolet (UV) to visible (cyan) is observed as a consequence of upward pKa shift of the drug inside the nano-cavity of cucurbit[7]uril.

Graphical abstract: Cucurbit[7]uril assisted ultraviolet to visible fluorescence switch of a heart medicine

Supplementary files

Article information

Article type
Communication
Submitted
20 Nov 2013
Accepted
23 Dec 2013
First published
02 Jan 2014

Phys. Chem. Chem. Phys., 2014,16, 2823-2826

Cucurbit[7]uril assisted ultraviolet to visible fluorescence switch of a heart medicine

K. Gavvala, R. K. Koninti, A. Sengupta and P. Hazra, Phys. Chem. Chem. Phys., 2014, 16, 2823 DOI: 10.1039/C3CP54895C

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