Jump to main content
Jump to site search

Issue 40, 2012
Previous Article Next Article

Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport

Author affiliations

Abstract

The structural core of DNA, a continuous stack of aromatic heterocycles, the base pairs, which extends down the helical axis, gives rise to the fascinating electronic properties of this molecule that is so critical for life. Our laboratory and others have developed diverse experimental platforms to investigate the capacity of DNA to conduct charge, termed DNA-mediated charge transport (DNA CT). Here, we present an overview of DNA CT experiments in solution, on surfaces, and with single molecules that collectively provide a broad and consistent perspective on the essential characteristics of this chemistry. DNA CT can proceed over long molecular distances but is remarkably sensitive to perturbations in base pair stacking. We discuss how this foundation, built with data from diverse platforms, can be used both to inform a mechanistic description of DNA CT and to inspire the next platforms for its study: living organisms and molecular electronics.

Graphical abstract: Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport

Back to tab navigation

Publication details

The article was received on 17 May 2012, accepted on 18 Jul 2012 and first published on 31 Jul 2012


Article type: Perspective
DOI: 10.1039/C2CP41602F
Citation: Phys. Chem. Chem. Phys., 2012,14, 13754-13771
  •   Request permissions

    Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport

    N. B. Muren, E. D. Olmon and J. K. Barton, Phys. Chem. Chem. Phys., 2012, 14, 13754
    DOI: 10.1039/C2CP41602F

Search articles by author

Spotlight

Advertisements