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Issue 48, 2017
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Iron-catalyzed C–H/N–H activation by triazole guidance: versatile alkyne annulation

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Abstract

Iron-catalyzed C–H/N–H functionalizations were achieved by the aid of modular triazole amides. The alkyne annulation allowed for the expedient synthesis of valuable isoquinolone scaffolds with high levels of chemo-, site- and regio-selectivities.

Graphical abstract: Iron-catalyzed C–H/N–H activation by triazole guidance: versatile alkyne annulation

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Publication details

The article was received on 01 May 2017, accepted on 22 May 2017 and first published on 23 May 2017


Article type: Communication
DOI: 10.1039/C7CC03376A
Citation: Chem. Commun., 2017,53, 6460-6463
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    Iron-catalyzed C–H/N–H activation by triazole guidance: versatile alkyne annulation

    G. Cera, T. Haven and L. Ackermann, Chem. Commun., 2017, 53, 6460
    DOI: 10.1039/C7CC03376A

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