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Issue 39, 2017
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Solid-phase synthesis of peptide selenoesters via a side-chain anchoring strategy

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Abstract

Peptide selenoesters have recently emerged as key building blocks for the ligation-based assembly of large polypeptides and proteins. Herein, we report an efficient solid-phase method for the high yielding and epimerisation-free synthesis of peptide selenoesters using a side-chain immobilisation strategy.

Graphical abstract: Solid-phase synthesis of peptide selenoesters via a side-chain anchoring strategy

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Publication details

The article was received on 31 Jan 2017, accepted on 24 Apr 2017 and first published on 24 Apr 2017


Article type: Communication
DOI: 10.1039/C7CC00823F
Citation: Chem. Commun., 2017,53, 5424-5427
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    Solid-phase synthesis of peptide selenoesters via a side-chain anchoring strategy

    C. C. Hanna, S. S. Kulkarni, E. E. Watson, B. Premdjee and R. J. Payne, Chem. Commun., 2017, 53, 5424
    DOI: 10.1039/C7CC00823F

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