Facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles for simultaneous imaging and pH/NIR-responsive drug delivery

Abstract

A facile one-pot synthetic strategy was explored to synthesize carbon/calcium phosphate/Fe₃O₄ composite nanoparticles (carbon/CaP/Fe₃O₄ composite NPs). Taking advantage of the unique structure including mesoporous, small CaP and Fe₃O₄ subunits homogeneously distributed in a carbon matrix, carbon/CaP/Fe₃O₄ NPs integrate high drug loading, pH/NIR-sensitive, photothermal and magnetic properties into one nanoplatform for cancer theranostics.