Issue 26, 2016

Enantioselective iridium-catalyzed hydrogenation of β,β-disubstituted nitroalkenes

Abstract

An iridium complex with a newly prepared chiral spiro amino-phosphine ligand efficiently catalyzed the hydrogenation of both β-aryl-β-methyl-nitroalkenes and β-alkyl-β-methyl-nitroalkenes to the corresponding saturated nitroalkanes, which represents the first report of a chiral catalyst that exhibits high enantioselectivity for the challenging hydrogenation of β,β-dialkyl-nitroalkenes.

Graphical abstract: Enantioselective iridium-catalyzed hydrogenation of β,β-disubstituted nitroalkenes

Supplementary files

Article information

Article type
Communication
Submitted
10 Feb 2016
Accepted
03 Mar 2016
First published
03 Mar 2016

Chem. Commun., 2016,52, 4812-4815

Enantioselective iridium-catalyzed hydrogenation of β,β-disubstituted nitroalkenes

Y. Yu, L. Cheng, Y. Li, Y. Fu, S. Zhu and Q. Zhou, Chem. Commun., 2016, 52, 4812 DOI: 10.1039/C6CC01273F

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