Issue 32, 2016

Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

Abstract

Lipidated DNAzymes or a lipidated Cu(II)-complex and lipidated aptamer sequences form supramolecular assemblies of micellar nucleoapzymes for the enhanced oxidation of dopamine to aminochrome. The catalytic functions of the micellar nucleoapzymes are attributed to the concentration of the substrate, using the aptamer units, in close proximity to the active sites.

Graphical abstract: Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

Supplementary files

Article information

Article type
Communication
Submitted
04 Feb 2016
Accepted
15 Mar 2016
First published
15 Mar 2016

Chem. Commun., 2016,52, 5561-5564

Supramolecular micelle-based nucleoapzymes for the catalytic oxidation of dopamine to aminochrome

H. B. Albada, J. W. de Vries, Q. Liu, E. Golub, N. Klement, A. Herrmann and I. Willner, Chem. Commun., 2016, 52, 5561 DOI: 10.1039/C6CC01115B

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