Issue 5, 2016

Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs

Abstract

We report the first successful implementation of transfection agents to facilitate the delivery of non-nucleic acid based anti-inflammatory and anti-viral drugs. In doing so, we illustrate a new paradigm in the intracellular delivery of polyanionic drugs and also extend the scope and utility of successful tools of gene transfer into a new area of biomedical research.

Graphical abstract: Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs

Supplementary files

Article information

Article type
Communication
Submitted
24 Sep 2015
Accepted
12 Nov 2015
First published
12 Nov 2015

Chem. Commun., 2016,52, 889-891

Author version available

Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs

M. B. L. Kryger, S. L. Pedersen, B. M. Wohl and A. N. Zelikin, Chem. Commun., 2016, 52, 889 DOI: 10.1039/C5CC08011H

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