Issue 9, 2016
From the journal:

Chemical Communications

Flexible DNA junction assisted efficient construction of stable gene nanoparticles for gene delivery†

Jianbing Liu,a   Yanyan Li,a   Dejun Ma,a   Di Ouyanga  and  Zhen Xi*a  

* Corresponding authors

a Department of Chemical Biology, State Key Laboratory of Elemento-Organic Chemistry, National Engineering Research Center of Pesticide (Tianjin), Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300071, China
E-mail: zhenxi@nankai.edu.cn
Tel: +86 22-2350-4782

Abstract

A flexible DNA junction was designed to assist the construction of stable gene nanoparticles with multiple target gene copies, which can be used as efficient gene cargo with successful expression in eukaryotic cells for gene delivery.

Graphical abstract: Flexible DNA junction assisted efficient construction of stable gene nanoparticles for gene delivery

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Article information

DOI
https://doi.org/10.1039/C5CC07949G
Article type
Communication
Submitted
22 Sep 2015
Accepted
09 Dec 2015
First published
11 Dec 2015

Chem. Commun., 2016,52, 1953-1956

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Flexible DNA junction assisted efficient construction of stable gene nanoparticles for gene delivery

J. Liu, Y. Li, D. Ma, D. Ouyang and Z. Xi, Chem. Commun., 2016, 52, 1953 DOI: 10.1039/C5CC07949G

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