Issue 23, 2015
From the journal:

Chemical Communications

Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release†

Hua Wang,a   Ming Xu,a   Menghua Xionga  and  Jianjun Cheng*ab  

* Corresponding authors

a Department of Materials Science and Engineering, University of Illinois at Urbana–Champaign, 1304 West Green Street, Urbana, IL, USA
E-mail: jianjunc@illinois.edu

b Department of Bioengineering, University of Illinois at Urbana–Champaign, 1304 West Green Street, Urbana, IL, USA

Abstract

Dithiomaleimide-based camptothecin-containing nanoparticles are designed to have exceptionally high drug loading and are capable of reduction-responsive, FRET-indicated drug release.

Graphical abstract: Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release

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Article information

DOI
https://doi.org/10.1039/C5CC00148J
Article type
Communication
Submitted
07 Jan 2015
Accepted
05 Feb 2015
First published
18 Feb 2015

Chem. Commun., 2015,51, 4807-4810

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Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release

H. Wang, M. Xu, M. Xiong and J. Cheng, Chem. Commun., 2015, 51, 4807 DOI: 10.1039/C5CC00148J

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