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Issue 2, 2015
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Signal enhancement of electrochemical biosensors via direct electrochemical oxidation of silver nanoparticle labels coated with zwitterionic polymers

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Abstract

A new electrochemical label has been developed, which is made up of silver nanoparticles (AgNPs) coated with a mixture of zwitterionic and biotinylated zwitterionic polymers. These polymers improve colloidal stability in physiological medium and ensure biorecognition while direct electrochemical oxidation of silver nanoparticles strongly enhances the detection signal. The resulting hybrid nanomaterials are used as labels in the electrochemical sensing of avidin using sandwich assays elaborated using the biotin–avidin biorecognition system.

Graphical abstract: Signal enhancement of electrochemical biosensors via direct electrochemical oxidation of silver nanoparticle labels coated with zwitterionic polymers

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Publication details

The article was received on 22 Sep 2014, accepted on 10 Nov 2014 and first published on 10 Nov 2014


Article type: Communication
DOI: 10.1039/C4CC07474B
Citation: Chem. Commun., 2015,51, 402-405
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    Signal enhancement of electrochemical biosensors via direct electrochemical oxidation of silver nanoparticle labels coated with zwitterionic polymers

    R. Geagea, P.-H. Aubert, P. Banet and N. Sanson, Chem. Commun., 2015, 51, 402
    DOI: 10.1039/C4CC07474B

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