Formal [3+3] cycloaddition of indol-2-yl carbinol with azadiene and the oxidative ring expansion reaction for the synthesis of indole azepinones†
Abstract
We present the unprecedented reaction of a [3+3] cyclization of indol-2-yl carbinol with azadiene for the construction of a six-membered ring and the subsequent oxidative ring expansion reaction for the construction of indole azepinones.