Issue 68, 2014

Rhodium-catalyzed direct synthesis of unprotected NH-sulfoximines from sulfoxides

Abstract

A novel rhodium-catalyzed imination of sulfoxides using O-(2,4-dinitrophenyl)hydroxylamine is developed under mild conditions with good functional group tolerance. This method provides an efficient access to free NH-sulfoximines, an important structural unit in a variety of biologically active compounds.

Graphical abstract: Rhodium-catalyzed direct synthesis of unprotected NH-sulfoximines from sulfoxides

Supplementary files

Article information

Article type
Communication
Submitted
07 Jun 2014
Accepted
02 Jul 2014
First published
03 Jul 2014

Chem. Commun., 2014,50, 9687-9689

Author version available

Rhodium-catalyzed direct synthesis of unprotected NH-sulfoximines from sulfoxides

J. Miao, N. G. J. Richards and H. Ge, Chem. Commun., 2014, 50, 9687 DOI: 10.1039/C4CC04349A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements