Issue 64, 2014
From the journal:

Chemical Communications

epi-Fluorescence imaging at the air–water interface of fibrillization of bovine serum albumin and human insulin†

Kristen Sessions,a   Stuart Sacks,a   Shanghao Lia  and  Roger M. Leblanc*a  

* Corresponding authors

a Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA
E-mail: rml@miami.edu
Fax: +1-305-284-4571
Tel: +1-305-284-2194

Abstract

Protein fibrillization is associated with many devastating neurodegenerative diseases. This process has been studied using spectroscopic and microscopic methods. In this study, epi-fluorescence at the air–water interface was developed as an innovative technique for observing fibrillization of bovine serum albumin and human insulin.

Graphical abstract: epi-Fluorescence imaging at the air–water interface of fibrillization of bovine serum albumin and human insulin

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Article information

DOI
https://doi.org/10.1039/C4CC04030A
Article type
Communication
Submitted
26 May 2014
Accepted
25 Jun 2014
First published
25 Jun 2014

Chem. Commun., 2014,50, 8955-8957

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epi-Fluorescence imaging at the air–water interface of fibrillization of bovine serum albumin and human insulin

K. Sessions, S. Sacks, S. Li and R. M. Leblanc, Chem. Commun., 2014, 50, 8955 DOI: 10.1039/C4CC04030A

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