NIR-triggered drug release from switchable rotaxane-functionalized silica-covered Au nanorods†
Abstract
An NIR-triggered drug delivery system was developed by capping photo-switchable azobenzene-based rotaxane onto Au nanorod–mesoporous silica core–shell hybrids. Drug release from the nanocarrier in zebrafish embryo models could be controlled remotely under NIR irradiation, showing significant drug spreading to the adjacent tissues.