Issue 54, 2014
From the journal:

Chemical Communications

Manganese porphyrin–double stranded DNA complex guided in situ deposition of polyaniline for electrochemical thrombin detection†

Shunbi Xie,a   Yaqin Chai,*a   Yali Yuana  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yqchai@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86-023-68254000
Tel: +86-023-68252277

Abstract

In this work, we proposed a novel electrochemical strategy for sensitive detection of thrombin (TB) based on in situ generation of polyaniline (PANI) as a redox mediator by using a manganese porphyrin–double stranded DNA (MnTMPyP–dsDNA) peroxidase-like artificial enzyme mimic as a powerful catalyst and template.

Graphical abstract: Manganese porphyrin–double stranded DNA complex guided in situ deposition of polyaniline for electrochemical thrombin detection

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Article information

DOI
https://doi.org/10.1039/C4CC02608J
Article type
Communication
Submitted
09 Apr 2014
Accepted
12 May 2014
First published
13 May 2014

Chem. Commun., 2014,50, 7169-7172

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Manganese porphyrin–double stranded DNA complex guided in situ deposition of polyaniline for electrochemical thrombin detection

S. Xie, Y. Chai, Y. Yuan and R. Yuan, Chem. Commun., 2014, 50, 7169 DOI: 10.1039/C4CC02608J

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