Novel syntheses of aryl quinoxaline C-nucleoside analogs by mild and efficient three-component sequential reactions†
Abstract
Novel syntheses of C-nucleoside analogs with aryl quinoxalines as nucleobase surrogates have been accomplished by mild and efficient three-component sequential reactions in high yields with a wide scope of substrates. The mechanism was clarified by isolation of novel sugar 1,2-diketone derived from oxidation of the corresponding alkyne.